Conditions: Lumbar Isthmic Spondylolisthesis (Adolescent) PDF Print E-mail

Keywords
Isthmic Spondylolisthesis
Sports Injury
Pars Fracture
Spine Fusion
Bracing

Definition
Isthmic Spondylolisthesis is the slippage of the top vertebra forward on the lower vertebra due to a fracture in the connecting area called the pars (pars interarticularis).

Indications
The indications for surgery in isthmic spondylolisthesis in adolescents is severe back pain with activity, leg pain, loss of control of the bowel and bladder, progressive muscle weakness in the leg or legs. Progression of the spondylolisthesis can be an indication also. Most adolescents with lower grade spondylolisthesis or spondylolysis are managed conservatively.

Technical Considerations



Pars Defect Repair Fusion in Situ Fusion with Reduction and Fixation
Posterolateral Fusion Only Posterolateral Fusion and Instrumentation Anterior Fusion only
Anterior Fusion and Posterolateral Fusion and Instrumentation Anterior Fusion and laminectomy and Posterolateral Fusion and Instrumentation


Literature Review
Featured Review:

The incidence of spondylolysis has been reviewed in separate studies. In one study, a significant number of athletes with low back pain were diagnosed with spondylolysis (pars fracture) under the age of 18. This is a common diagnosis in teenage athletes.(ref #14)



100 patients with low back pain reviewed in a sports clinic under 18 100 patients with low back pain reviewed in a sports clinic over 18
47% spondylolysis (pars fracture) 5% spondylolysis (pars fracture)


The development of sponylolysis is due to biomechanical vulnerability of the area that develops the fracture (ref #39, ref #53, ref #59, ref #62, ref #63). This concept provides that the pars is thin, the posterior arch is not at maximum strength and the disc is less resistant to shear force. In additon, extension sports are involved (gymnastics, etc) due to shear stresses in the pars with extension of the spine and repeated microfracture with repeated extension (ref #39, ref #40, ref #45)

The clinical pattern could involve the following anatomic combinations.



unilateral stress reaction unilateral pars defect and contralateral stress reaction
bilateral stress reaction bilateral pars defects with unilateral stress reaction above or below Spondylolisthesis at a single level or multiple levels
unilateral pars defect bilateral pars defects with bilateral stress reactions above or below Spondylolisthesis and other defect or stress reaction patterns
bilateral pars defects unilateral pars defect and unilateral or bilateral stess reaction above or below


A stress reaction in bone is an impending stress fracture and may be detected on a SPECT scan. A pars defect is a formal fracture through the anatomic zone called the pars interarticularis.

Many patients with an acute pars fracture can be treated conservatively with bracing, temporary restriction of activity, and physical therapy. The vast majority of patients improve and return to sports (ref #24). The statistical progression of low grade slips is low and once symptoms are resolved the majority of adolescents return to their sport (ref #6, ref #9).The lower grade slips are grade I and II, the higher grade slips are III and IV.

Surgical management of lower grade slips can involve direct repair of the pars fracture (ref #1, ref #2, ref #3, ref #10, ref #12, ref #17, ref #21, ref #22, ref #23, ref #27, ref #28, ref # 32, ref #41, ref #49) or fusion in the postion of the slip or with reduction of the slip to normal anatomic position (ref #29, ref #30, ref #35, ref #37, ref #47, ref #54). The results of surgery are in general good for low grade slips. Higher grade slips often involve greater magnitude of surgery and the results depend on the preoperative condition of the patient and the nature of the partiuclar operation employed (ref #5, ref #7, ref #11, ref #13, ref #25, ref #31, ref #36, ref #42, ref #44, ref #46, ref #55, ref #56, ref #57).

Complications
Complications in surgery for adolescent spondylolisthesis depend on the grade of the slip and the nature of the operation and surgical approach. The general risks of spine surgery are death, paralysis, failure to improve, failure to fuse, hardware failure, nerve root injury, spinal fluid leak, infection, etc.

Author’s Comment
The diagnosis of stress fractures (stress reaction in bone) in adolescent athletes is often made on a SPECT scan. The completed pars defects (completed fractures) are found on CAT scans. The presence of a slip implies the presence of the pars fractures in this age group in the overwhelming majority of cases. Most athletes can be treated non-operatively with a good prognosis. Occasionally, direct repair of the pars defects or a posterolateral fusion are necessary to provide symptom relief. The more advanced slips (grade III and IV) may require more significant surgery.

References

1. Sales de Gauzy, J., F. Vadier, and J.P. Cahuzac, Repair of lumbar spondylolysis using Morscher material: 14 children followed for 1-5 years. Acta Orthop Scand, 2000. 71(3): p. 292-6.
2. Pellise, F., et al., Clinical and CT scan evaluation after direct defect repair in spondylolysis using segmental pedicular screw hook fixation. J Spinal Disord, 1999. 12(5): p. 363-7.
3. Gillet, P. and M. Petit, Direct repair of spondylolysis without spondylolisthesis, using a rod-screw construct and bone grafting of the pars defect. Spine, 1999. 24(12): p. 1252-6.
4. Lonstein, J.E., Spondylolisthesis in children. Cause, natural history, and management. Spine, 1999. 24(24): p. 2640-8.
5. Roca, J., et al., One-stage decompression and posterolateral and interbody fusion for severe spondylolisthesis. An analysis of 14 patients. Spine, 1999. 24(7): p. 709-14.
6. Congeni, J., J. McCulloch, and K. Swanson, Lumbar spondylolysis. A study of natural progression in athletes. Am J Sports Med, 1997. 25(2): p. 248-53.
7. Muschik, M., H. Zippel, and C. Perka, Surgical management of severe spondylolisthesis in children and adolescents. Anterior fusion in situ versus anterior spondylodesis with posterior transpedicular instrumentation and reduction. Spine, 1997. 22(17): p. 2036-42; discussion 2043.
8. Seitsalo, S., et al., Disc degeneration in young patients with isthmic spondylolisthesis treated operatively or conservatively: a long-term follow-up. Eur Spine J, 1997. 6(6): p. 393-7.
9. Muschik, M., et al., Competitive sports and the progression of spondylolisthesis. J Pediatr Orthop, 1996. 16(3): p. 364-9.
10. Tokuhashi, Y. and H. Matsuzaki, Repair of defects in spondylolysis by segmental pedicular screw hook fixation. A preliminary report. Spine, 1996. 21(17): p. 2041-5.
11. Fabris, D.A., S. Costantini, and U. Nena, Surgical treatment of severe L5-S1 spondylolisthesis in children and adolescents. Results of intraoperative reduction, posterior interbody fusion, and segmental pedicle fixation. Spine, 1996. 21(6): p. 728-33.
12. Jeanneret, B., et al., Posterior stabilization in L5-S1 isthmic spondylolisthesis with paralaminar screw fixation: anatomical and clinical results. J Spinal Disord, 1996. 9(3): p. 223-33.
13. Tiusanen, H., et al., Results of a trial of anterior or circumferential lumbar fusion in the treatment of severe isthmic spondylolisthesis in young patients. J Pediatr Orthop B, 1996. 5(3): p. 190-4.
14. Micheli, L.J. and R. Wood, Back pain in young athletes. Significant differences from adults in causes and patterns. Arch Pediatr Adolesc Med, 1995. 149(1): p. 15-8.
15. Ricciardi, J.E., et al., Transpedicular fixation for the treatment of isthmic spondylolisthesis in adults. Spine, 1995. 20(17): p. 1917-22.
16. Green, T.P., J.C. Allvey, and M.A. Adams, Spondylolysis. Bending of the inferior articular processes of lumbar vertebrae during simulated spinal movements. Spine, 1994. 19(23): p. 2683-91.
17. Tonino, A. and G. van der Werf, Direct repair of lumbar spondylolysis. 10-year follow-up of 12 previously reported cases. Acta Orthop Scand, 1994. 65(1): p. 91-3.
18. Axelsson, P., et al., Posterolateral lumbar fusion. Outcome of 71 consecutive operations after 4 (2-7) years. Acta Orthop Scand, 1994. 65(3): p. 309-14.
19. Laus, M., et al., Posterolateral spinal fusion: a study of 123 cases with a long-term follow-up. Chir Organi Mov, 1994. 79(1): p. 69-79.
20. Marchetti, P.G., et al., The surgical treatment of spondylolisthesis. Chir Organi Mov, 1994. 79(1): p. 85-91.
21. Pavlovcic, V., Surgical treatment of spondylolysis and spondylolisthesis with a hook screw. Int Orthop, 1994. 18(1): p. 6-9.
22. Hardcastle, P.H., Repair of spondylolysis in young fast bowlers. J Bone Joint Surg Br, 1993. 75(3): p. 398-402.
23. Jeanneret, B., Direct repair of spondylolysis. Acta Orthop Scand Suppl, 1993. 251: p. 111-5.
24. Blanda, J., et al., Defects of pars interarticularis in athletes: a protocol for nonoperative treatment. J Spinal Disord, 1993. 6(5): p. 406-11.
25. Poussa, M., et al., Surgical treatment of severe isthmic spondylolisthesis in adolescents. Reduction or fusion in situ. Spine, 1993. 18(7): p. 894-901.
26. Raby, N. and S. Mathews, Symptomatic spondylolysis: correlation of CT and SPECT with clinical outcome. Clin Radiol, 1993. 48(2): p. 97-9.
27. Johnson, G.V. and A.G. Thompson, The Scott wiring technique for direct repair of lumbar spondylolysis. J Bone Joint Surg Br, 1992. 74(3): p. 426-30.
28. Hefti, F., W. Seelig, and E. Morscher, Repair of lumbar spondylolysis with a hook-screw. Int Orthop, 1992. 16(1): p. 81-5.
29. Burkus, J.K., et al., Long-term evaluation of adolescents treated operatively for spondylolisthesis. A comparison of in situ arthrodesis only with in situ arthrodesis and reduction followed by immobilization in a cast. J Bone Joint Surg Am, 1992. 74(5): p. 693-704.
30. Lenke, L.G., et al., Results of in situ fusion for isthmic spondylolisthesis. J Spinal Disord, 1992. 5(4): p. 433-42.
31. Schwend, R.M., et al., Treatment of severe spondylolisthesis in children by reduction and L4-S4 posterior segmental hyperextension fixation. J Pediatr Orthop, 1992. 12(6): p. 703-11.
32. Bonnici, A.V., S.R. Koka, and D.J. Richards, Results of Buck screw fusion in grade I spondylolisthesis. J R Soc Med, 1991. 84(5): p. 270-3.
33. Markwalder, T.M., C. Saager, and H.J. Reulen, "Isthmic" spondylolisthesis--an analysis of the clinical and radiological presentation in relation to intraoperative findings and surgical results in 72 consecutive cases. Acta Neurochir (Wien), 1991. 110(3-4): p. 154-9.
34. Seitsalo, S., et al., Progression of spondylolisthesis in children and adolescents. A long-term follow-up of 272 patients. Spine, 1991. 16(4): p. 417-21.
35. Vanden Berghe, L., et al., In situ posterolateral fusion for spondylolisthesis. Acta Orthop Belg, 1991. 57(Suppl 1): p. 214-8.
36. Bradford, D.S. and O. Boachie-Adjei, Treatment of severe spondylolisthesis by anterior and posterior reduction and stabilization. A long-term follow-up study. J Bone Joint Surg Am, 1990. 72(7): p. 1060-6.
37. Lindholm, T.S., et al., Lumbar isthmic spondylolisthesis in children and adolescents. Radiologic evaluation and results of operative treatment. Spine, 1990. 15(12): p. 1350-5.
38. Seitsalo, S., et al., Severe spondylolisthesis in children and adolescents. A long-term review of fusion in situ. J Bone Joint Surg Br, 1990. 72(2): p. 259-65.
39. Hensinger, R.N., Spondylolysis and spondylolisthesis in children and adolescents. J Bone Joint Surg Am, 1989. 71(7): p. 1098-107.
40. Weir, M.R. and D.S. Smith, Stress reaction of the pars interarticularis leading to spondylolysis. A cause of adolescent low back pain. J Adolesc Health Care, 1989. 10(6): p. 573-7.
41. Roca, J., et al., Direct repair of spondylolysis. Clin Orthop, 1989(246): p. 86-91.
42. Dick, W.T. and B. Schnebel, Severe spondylolisthesis. Reduction and internal fixation. Clin Orthop, 1988(232): p. 70-9.
43. Johnson, L.P., R.J. Nasca, and W.K. Dunham, Surgical management of isthmic spondylolisthesis. Spine, 1988. 13(1): p. 93-7.
44. Bradford, D.S. and Y. Gotfried, Staged salvage reconstruction of grade-IV and V spondylolisthesis. J Bone Joint Surg Am, 1987. 69(2): p. 191-202.
45. Letts, M., et al., Fracture of the pars interarticularis in adolescent athletes: a clinical-biomechanical analysis. J Pediatr Orthop, 1986. 6(1): p. 40-6.
46. Matthiass, H.H. and J. Heine, The surgical reduction of spondylolisthesis. Clin Orthop, 1986(203): p. 34-44.
47. Pizzutillo, P.D., W. Mirenda, and G.D. MacEwen, Posterolateral fusion for spondylolisthesis in adolescence. J Pediatr Orthop, 1986. 6(3): p. 311-6.
48. Steiner, M.E. and L.J. Micheli, Treatment of symptomatic spondylolysis and spondylolisthesis with the modified Boston brace. Spine, 1985. 10(10): p. 937-43.
49. van der Werf, G.J., A.J. Tonino, and W.S. Zeegers, Direct repair of lumbar spondylolysis. Acta Orthop Scand, 1985. 56(5): p. 378-9.
50. Suzuki, T., et al., Posterior intertransverse fusion assessed clinically and with biplanar radiography. Int Orthop, 1985. 9(1): p. 11-7.
51. Savini, R., et al., Posterolateral lumbosacral arthrodesis (P.L.A.). A study of 85 cases. Ital J Orthop Traumatol, 1984. 10(4): p. 449-60.
52. Bradford, D.S., Management of spondylolysis and spondylolisthesis. Instr Course Lect, 1983. 32: p. 151-62.
53. Hensinger, R.N., Spondylolysis and spondylolisthesis in children. Instr Course Lect, 1983. 32: p. 132-51.
54. Johnson, J.R. and E.O. Kirwan, The long-term results of fusion in situ for severe spondylolisthesis. J Bone Joint Surg Br, 1983. 65(1): p. 43-6.
55. Bohlman, H.H. and S.S. Cook, One-stage decompression and posterolateral and interbody fusion for lumbosacral spondyloptosis through a posterior approach. Report of two cases. J Bone Joint Surg Am, 1982. 64(3): p. 415-8.
56. van Rens, T.J. and J.R. van Horn, Long-term results in lumbosacral interbody fusion for spondylolisthesis. Acta Orthop Scand, 1982. 53(3): p. 383-92.
57. DeWald, R.L., et al., Severe lumbosacral spondylolisthesis in adolescents and children. Reduction and staged circumferential fusion. J Bone Joint Surg Am, 1981. 63(4): p. 619-26.
58. Sevastikoglou, J.A., E. Spangfort, and S. Aaro, Operative treatment of spondylolisthesis in children and adolescents with tight hamstrings syndrome. Clin Orthop, 1980(147): p. 192-9.
59. Cyron, B.M., W.C. Hutton, and J.R. Stott, Spondylolysis: the shearing stiffness of the lumbar intervertebral joint. Acta Orthop Belg, 1979. 45(4): p. 459-69.
60. Jakab, G. and A. Eross, Loading bearing of the lumbar vertebral arch. Acta Chir Acad Sci Hung, 1979. 20(4): p. 407-18.
61. Boxall, D., et al., Management of severe spondylolisthesis in children and adolescents. J Bone Joint Surg Am, 1979. 61(4): p. 479-95.
62. Hutton, W.C. and B.M. Cyron, Spondyloysis. The role of the posterior elements in resisting the intervertebral compressive force. Acta Orthop Scand, 1978. 49(6): p. 604-9.
63. Troup, J.D., The etiology of spondylolysis. Orthop Clin North Am, 1977. 8(1): p. 57-64.


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